The Utility of Galectin-3 and HBME-1 Immunohistochemical Expression in Thyroid Cancer in the Maltese Population

Diagnosing thyroid carcinoma is not always easy on basic haemtoxylin and eosin staining since nuclear features are inconsistent controversial. In view of this, studies the role immunohistochemical markers in diagnosis malignant necessary. Proposed for papillary cancer include Hector Battifora mesothelial-1 (HBME-1), Galectin-3 (Gal-3) which have been studied this project. Immunohistochemical fifty-eight formalin-fixed paraffin embedded surgically removed tissue from years 2008 2013 was undertaken to determine diagnostic accuracy these two markers. We concluded that both Gal-3 HBME-1 useful aid also distinguishing between benign lesions. The sensitivity specificity over 2years found be 96.2% 92.6%, respectively, whilst 93.6% 69.02%.